Prognostic value of chest computer tomography combined with serum platelet count, c-reactive protein levels and oxygenation index in severe community-acquired pneumonia

Yun Wu; Sijie Xu; Yi Xia

doi:10.12669/pjms.41.2.10405

Yun Wu
Sijie Xu
Yi Xia Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University

DOI: https://doi.org/10.12669/pjms.41.2.10405

Keywords: chest CT, platelet count, C-reactive protein, oxygenation index, severe pneumonia, Severe community-acquired pneumonia

Abstract

Objective: To investigate the prognostic value of chest computed tomography (CT), platelet count (PLT), serum C-reactive protein (CRP) level, and oxygenation index (OI) in patients with severe community-acquired pneumonia (CAP).

Methods: We conducted a retrospective analysis of clinical data collected from 226 patients with CAP who received treatment in Huzhou Central Hospital from February 2022 to November 2023. Patients were divided into two groups based on pneumonia severity: Severe group (patients with severe CAP, n=113) and Typical group (patients with typical pneumonia, n=113). Differences in CT score, PLT, CRP, and OI levels between the two groups were analyzed, as well as the prognostic value of the combined CT score, PLT, CRP, and OI levels in severe CAP.

Results: The CT Score and CRP level in the Severe group were significantly higher than those in the Typical group, whereas PLT and OI were significantly lower (P<0.05). Of 113 patients with severe pneumonia, 42 died and 71 survived. The CT Score and CRP level in the death group were significantly higher, whereas PLT and OI were lower compared to the survival group (P<0.05). The area under the ROC curve of the combined CT Score, PLT, CRP, OI for the prediction of death in patients with severe CAP was 0.970, sensitivity was 85.7, and specificity was 93.0, which was higher than that of each index alone.

Conclusions: The combined chest CT, PLT, CRP, and OI have high prognostic value for severe CAP.

doi: https://doi.org/10.12669/pjms.41.2.10405

How to cite this: Wu Y, Xu S, Xia Y. Prognostic value of chest computer tomography combined with serum platelet count, c-reactive protein levels and oxygenation index in severe community-acquired pneumonia. Pak J Med Sci. 2025;41(2):554-558. doi: https://doi.org/10.12669/pjms.41.2.10405

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.