Impact of academic center for evidence-based practice star model on door-to-needle times in patients with acute ischemic stroke

Zhen Li; Lili Zheng; Junke Zheng; Meiping Zhao

doi:10.12669/pjms.41.3.11056

Zhen Li A Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Lili Zheng
Junke Zheng
Meiping Zhao

DOI: https://doi.org/10.12669/pjms.41.3.11056

Keywords: Academic center for evidence-based practice star model, Acute ischemic stroke, Door-to-needle times

Abstract

Objective: To explore the impact of the academic center for evidence-based practice (ACE) star model on the door-to-needle times (DNT) in patients with acute ischemic stroke (AIS).

Methods: Clinical data of 159 patients with AIS, treated in Sir Run Run Shaw Hospital Afffliated to Zhejiang University School of Medicine Alar Hospital from March 2022 to March 2024, were retrospectively analyzed. Seventy-eight patients received routine care (routine group), and 81 patients were treated using a combination of routine care with the ACE star model (ACE star group). Operating time, intervention effects, activities of daily living (ADL), neurologic outcomes, and incidence of adverse events of the two groups were compared.

Results: The duration of venous opening, computed tomography (CT) examination, and DNT in the ACE star group were shorter than those in the routine group (P<0.05). The DNT<45 minutes compliance rate, thrombolytic efficacy, and vascular recanalization in the ACE star group were higher than those in the Routine group (P<0.05). After the intervention, the ADL score of the ACE star group was significantly higher than that of the control group, while the NIHSS score was significantly lower than that of the control group (P<0.05). There was no significant difference in the incidence of adverse events between the two groups (P>0.05).

Conclusions: Adopting routine nursing care and intervention based on the ACE-star model for patients with AIS can shorten DNT, improve thrombolytic effect and vascular recanalization rate. ACE-star model is beneficial for restoring ADL ability and improving neurological function, without significant changes in the occurrence of adverse events.

doi: https://doi.org/10.12669/pjms.41.3.11056

How to cite this: Li Z, Zheng L, Zheng J, Zhao M. Impact of academic center for evidence-based practice star model on door-to-needle times in patients with acute ischemic stroke. Pak J Med Sci. 2025;41(3):662-667. doi: https://doi.org/10.12669/pjms.41.3.11056

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