Knowledge, Attitude and Perception of Research Ethics and Research Ethics Committees among Post-Graduate Residents of Neurosciences - A Nationwide Analysis from Pakistan

Abstract

Objectives: To assess the knowledge, attitude and perception of post-graduate residents of neurosciences towards research ethics (RE) and research ethics committees (RECs).

Methods: This prospective cross-sectional survey-based study was conducted by the Punjab Institute of Neurosciences, targeting post-graduate neuroscience residents throughout Pakistan during January and February, 2024. An English-language general questionnaire, designed to assess knowledge, attitudes, and perceptions of RE and RECs, was adapted to reflect local conditions. The collected responses were analyzed using the Statistical Package for Social Sciences (SPSS) to determine measures of central tendency, percentages, and frequencies.

Results: Out of 241 residents, 64.3% were males. Sixty-eight percent respondents were from neurosurgery and 32% were from the field of neurology. Approximately 47% responses were from the province of Punjab. More than half (51.5%) of participants acknowledged the existence of a REC within their institution. A similar proportion (52.3%) claimed familiarity with ethical guidelines for research involving human subjects, only a slight majority (48.5%) demonstrated awareness of the specific functions carried out by RECs. Meanwhile, 44.5% expressed concerns that undergoing review by a REC could potentially delay research and pose additional challenges for researchers. Additionally, 27.4% of respondents admitted to considering the fabrication of data or results as acceptable.

Conclusion: Our research uncovered a significant correlation between participants’ perceptions of RE and RECs and their comprehension of ethical principles. These findings indicate that medical postgraduates with a deeper understanding or awareness of research ethics principles and RECs tend to hold more robust attitudes toward these aspects.

List of Abbreviations:
AAHRPP: Association for the Accreditation of Human Research Protection Program, DME: Department of Medical Education, DRAP-CSC: Drug Regulatory Authority of Pakistan-Clinical Studies Committee, FCPS: Fellow of College of Physicians and Surgeons, IRBs: Institutional Review Boards, LMICs: Low-Middle-Income Countries, MCQs: Multiple Choice Questions, MD: Master of Medicine, MS: Master of Surgery, NBC-REC: National Bioethics Committee-Research Ethics Committee, PMDC: Pakistan Medical and Dental Council, RE: Research Ethics, RECs: Research Ethics Committees, SPSS: Statistical Package for Social Sciences.

doi: https://doi.org/10.12669/pjms.40.12(PINS).11116

How to cite this: Qadri HM, Shahid R, Fatima SB, Naveed N, Khizar A, Siraj ul Haq, et al. Knowledge, Attitude and Perception of Research Ethics and Research Ethics Committees among Post-Graduate Residents of Neurosciences - A Nationwide Analysis from Pakistan. Pak J Med Sci. 2024;40(12):S55-S62. doi: https://doi.org/10.12669/pjms.40.12(PINS).11116

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